PTEN in prefrontal cortex is essential in regulating depression-like behaviors in mice

Abstract Chronic stress is an environmental risk factor for depression and causes neuronal atrophy in the prefrontal cortex (PFC) and other brain regions. It is still unclear about the molecular mechanism underlying the behavioral alterations and neuronal atrophy induced by chronic stress. We here r...

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Bibliographic Details
Main Authors: Xiao-Qing Wang, Lei Zhang, Zhong-Yuan Xia, Jia-Yin Chen, Yiru Fang, Yu-Qiang Ding
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01312-y