Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity.

Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity.

SKN-1, the Caenorhabditis elegans Nrf1/2/3 ortholog, promotes both oxidative stress resistance and longevity. SKN-1 responds to oxidative stress by upregulating genes that detoxify and defend against free radicals and other reactive molecules, a SKN-1/Nrf function that is both well-known and conserv...

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Bibliographic Details
Main Authors: Xuan Li, Olli Matilainen, Congyu Jin, Kira M Glover-Cutter, Carina I Holmberg, T Keith Blackwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3111486?pdf=render

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http://europepmc.org/articles/PMC3111486?pdf=render

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