Retinal dysfunction, photoreceptor protein dysregulation and neuronal remodelling in the R6/1 mouse model of Huntington's disease

Retinal dysfunction, photoreceptor protein dysregulation and neuronal remodelling in the R6/1 mouse model of Huntington's disease

Huntington's disease (HD) is a progressive neurological disease characterised by motor dysfunction, cognitive impairment and personality changes. Previous work in HD patients and animal models of the disease has also highlighted retinal involvement. This study characterised the changes in retin...

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Bibliographic Details
Main Authors: Abrez Hussain Batcha, Una Greferath, Andrew I. Jobling, Kirstan A. Vessey, Michelle M. Ward, Jess Nithianantharajah, Anthony J. Hannan, Michael Kalloniatis, Erica L. Fletcher
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Neurobiology of Disease
Subjects:
Retina
Huntington's disease
Photoreceptor
Cone opsin
Remodelling
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111003792

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http://www.sciencedirect.com/science/article/pii/S0969996111003792

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