The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodeling.

NOD1 is an intracellular pathogen recognition receptor that contributes to anti-bacterial innate immune responses, adaptive immunity and tissue homeostasis. NOD1-induced signaling relies on actin remodeling, however, the details of the connection of NOD1 and the actin cytoskeleton remained elusive....

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Bibliographic Details
Main Authors: Harald Bielig, Katja Lautz, Peter R Braun, Maureen Menning, Nikolaus Machuy, Christine Brügmann, Sandra Barisic, Stephan A Eisler, Maria Andree, Birte Zurek, Hamid Kashkar, Philippe J Sansonetti, Angelika Hausser, Thomas F Meyer, Thomas A Kufer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4154870?pdf=render