The TRPC6-AMPK Pathway is Involved in Insulin-Dependent Cytoskeleton Reorganization and Glucose Uptake in Cultured Rat Podocytes

The TRPC6-AMPK Pathway is Involved in Insulin-Dependent Cytoskeleton Reorganization and Glucose Uptake in Cultured Rat Podocytes

Background/Aims: Podocytes are dynamic polarized cells on the surface of glomerular capillaries that are an essential part of the glomerular filtration barrier. AMP-activated protein kinase (AMPK), a key regulator of glucose and fatty acid metabolism, plays a major role in obesity and type 2 diabete...

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Bibliographic Details
Main Authors: Patrycja Rachubik, Maria Szrejder, Dorota Rogacka, Irena Audzeyenka, Michał Rychłowski, Stefan Angielski, Agnieszka  Piwkowska
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
AMP-activated protein kinase
Calcium
Cytoskeleton
Glucose uptake
Insulin
Rho family of GTPases
Online Access:https://www.karger.com/Article/FullText/495236

Internet

https://www.karger.com/Article/FullText/495236

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