Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.

Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.

Methylenetetrahydrofolate reductase (MTHFR) is one of the enzymes involved in homocysteine metabolism. Despite considerable genetic and clinical attention, the reaction mechanism and regulation of this enzyme are not fully understood because of difficult production and poor stability. While recombin...

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Bibliographic Details
Main Authors: Sayaka Igari, Akashi Ohtaki, Yasuaki Yamanaka, Yuichi Sato, Masafumi Yohda, Masafumi Odaka, Keiichi Noguchi, Kazuhiro Yamada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3156243?pdf=render

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http://europepmc.org/articles/PMC3156243?pdf=render

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