Counter-Balance Between Gli3 and miR-7 Is Required for Proper Morphogenesis and Size Control of the Mouse Brain

Counter-Balance Between Gli3 and miR-7 Is Required for Proper Morphogenesis and Size Control of the Mouse Brain

Brain morphogenesis requires precise regulation of multiple genes to control specification of distinct neural progenitors (NPs) and neuronal production. Dysregulation of these genes results in severe brain malformation such as macrocephaly and microcephaly. Despite studies of the effect of individua...

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Bibliographic Details
Main Authors: Longbin Zhang, Taufif Mubarak, Yase Chen, Trevor Lee, Andrew Pollock, Tao Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Gli3
miR-7
cortical morphogenesis
brain size
neural progenitor
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00259/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00259/full

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