Thymic Function as a Predictor of Immune Recovery in Chronically HIV-Infected Patients Initiating Antiretroviral Therapy

Thymic Function as a Predictor of Immune Recovery in Chronically HIV-Infected Patients Initiating Antiretroviral Therapy

Poor immunological responders (PIR) are HIV-infected patients with virologic suppression upon antiretroviral therapy (ART) but persistently low CD4+ T cell counts. Early identification of PIR is important given their higher morbimortality compared to adequate immune responders (AIR). In this study,...

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Bibliographic Details
Main Authors: Rita Rb-Silva, Claudia Nobrega, Cecilia Azevedo, Emilia Athayde, João Canto-Gomes, Ivo Ferreira, Rémi Cheynier, Andrew J. Yates, Ana Horta, Margarida Correia-Neves
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
poor immunological responders
predictive modeling
immune recovery
cd4+ t cells
thymic function
immune activation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00025/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00025/full

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