RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.

The naked mole-rat (Heterocephalus glaber) is a long-lived, cancer resistant rodent and there is a great interest in identifying the adaptations responsible for these and other of its unique traits. We employed RNA sequencing to compare liver gene expression profiles between naked mole-rats and wild...

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Bibliographic Details
Main Authors: Chuanfei Yu, Yang Li, Andrew Holmes, Karol Szafranski, Chris G Faulkes, Clive W Coen, Rochelle Buffenstein, Matthias Platzer, João Pedro de Magalhães, George M Church
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3207814?pdf=render