Conversion of n-3 polyunsaturated fatty acids (PUFAs) and incorporation of docosahexaenoic acid (DHA) in cultured neural cells

Conversion of n-3 polyunsaturated fatty acids (PUFAs) and incorporation of docosahexaenoic acid (DHA) in cultured neural cells

Docosahexaenoic acid (DHA, 22:6n-3) in membrane phospholipids originates from dietary intake of preformed DHA and from conversion of its essential precursor α-linolenic acid (ALA, 18:3n-3). Cultured cells, especially nervous cells, are increasingly used to explore the uptake, metabolism and gene tra...

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Bibliographic Details
Main Authors: Alessandri Jean-Marc, Langelier Bénédicte, Perruchot Marie-Hélène, Extier Audrey, Pifferi Fabien, Jouin Mélanie, Delpal Serge, Lavialle Monique, Guesnet Philippe
Format: Article
Language:English
Published: EDP Sciences 2007-05-01
Series:Oléagineux, Corps gras, Lipides
Subjects:
docosahexaenoic acid (DHA)
endothelial cells
ethanolamine phosphoglycerolipids (EPG)
n-3 PUFA conversion
peroxisomal enzymes
rat brain
SH-SY5Y neuroblastoma cells
Online Access:http://dx.doi.org/10.1051/ocl.2007.0113

Internet

http://dx.doi.org/10.1051/ocl.2007.0113

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