Characterization of Pancreatic Cancer Tissue Using Multiphoton Excitation Fluorescence and Polarization-Sensitive Harmonic Generation Microscopy

Characterization of Pancreatic Cancer Tissue Using Multiphoton Excitation Fluorescence and Polarization-Sensitive Harmonic Generation Microscopy

Thin tissue sections of normal and tumorous pancreatic tissues stained with hematoxylin and eosin were investigated using multiphoton excitation fluorescence (MPF), second harmonic generation (SHG), and third harmonic generation (THG) microscopies. The cytoplasm, connective tissue, collagen and extr...

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Bibliographic Details
Main Authors: Danielle Tokarz, Richard Cisek, Ariana Joseph, Ahmad Golaraei, Kamdin Mirsanaye, Serguei Krouglov, Sylvia L. Asa, Brian C. Wilson, Virginijus Barzda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
collagen
optical pathology
medical imaging
non-linear optical polarimetry
non-linear optical microscopy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00272/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00272/full

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