Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

<h4>Objective</h4>Many patients with rheumatoid arthritis (RA) benefit from tumor necrosis factor-α blocking treatment (anti-TNF), but about one third do not respond. The objective of this study was to replicate and extend previously found associations between anti-TNF treatment response...

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Bibliographic Details
Main Authors: Jacob Sode, Ulla Vogel, Steffen Bank, Paal Skytt Andersen, Marianne Kragh Thomsen, Merete Lund Hetland, Henning Locht, Niels H H Heegaard, Vibeke Andersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24967817/?tool=EBI