Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G<sub>1 </sub>checkpoint function
<p>Abstract</p> <p>Background</p> <p>Secondary cultures of human fibroblasts display a finite lifespan ending at senescence. Loss of p53 function by mutation or viral oncogene expression bypasses senescence, allowing cell division to continue for an additional 10 – 20 d...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2005-10-01
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| Series: | Journal of Carcinogenesis |
| Online Access: | http://www.carcinogenesis.com/content/4/1/18 |