Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia

<p>Abstract</p> <p>Optimal conditioning therapy for hematopoietic cell transplantation (HCT) in acute myelogenous leukemia (AML) remains undefined. We retrospectively compared outcomes of a consecutive series of 51 AML patients treated with oral busulfan (1 mg/kg every 6 hours for...

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Bibliographic Details
Main Authors: Nishihori Taiga, Kharfan-Dabaja Mohamed A, Anasetti Claudio, Kim Jongphil, Pidala Joseph, Field Teresa, Perkins Janelle, Perez Lia, Fernandez Hugo F
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/3/1/36