Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease

Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease

Abstract Background Multiple sclerosis is a neuroinflammatory demyelinating and neurodegenerative disease of the central nervous system characterized by recurrent and progressive demyelination/remyelination cycles, neuroinflammation, oligodendrocyte loss, demyelination, and axonal degeneration. Cycl...

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Bibliographic Details
Main Authors: Shinji Yamamoto, Kota Yamashina, Masaki Ishikawa, Mari Gotoh, Sosuke Yagishita, Kensuke Iwasa, Kei Maruyama, Kimiko Murakami-Murofushi, Keisuke Yoshikawa
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Neuroinflammation
Subjects:
Cuprizone
Demyelination
Experimental autoimmune encephalomyelitis (EAE)
Microglia
Multiple sclerosis
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s12974-017-0923-5

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http://link.springer.com/article/10.1186/s12974-017-0923-5

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