Selection of phage-displayed human antibody fragments specific for CD1b presenting the Mycobacterium tuberculosis glycolipid Ac2SGL

Selection of phage-displayed human antibody fragments specific for CD1b presenting the Mycobacterium tuberculosis glycolipid Ac2SGL

Objective/background: The development of new tools capable of targeting Mycobacterium tuberculosis (Mtb)-infected cells have potential applications in diagnosis, treatment, and prevention of tuberculosis. In Mtb-infected cells, CD1b molecules present Mtb lipids to the immune system (Mtb lipid–CD1b c...

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Bibliographic Details
Main Authors: Frank Camacho, María E Sarmiento, Fatima Reyes, Louise Kim, Jim Huggett, Marco Lepore, Oscar Otero, Martine Gilleron, Germain Puzo, Mohd Nor Norazmi, Graham Rook, Lucia Mori, Gennaro De Libero, Armando Acosta
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:International Journal of Mycobacteriology
Subjects:
Antibodies
CD1b
Lipids
Tuberculosis
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=2;spage=120;epage=127;aulast=Camacho

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http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=2;spage=120;epage=127;aulast=Camacho

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