Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia.

Pancreatic acinar-to-ductal metaplasia (ADM) is associated with an increased risk of pancreatic cancer and is considered a precursor of pancreatic ductal adenocarcinoma. Transgenic expression of transforming growth factor alpha (TGF-α) or K-ras(G12D) in mouse pancreatic epithelium induces ADM in viv...

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Bibliographic Details
Main Authors:	Michele L Scotti, Kristin E Smith, Amanda M Butler, Shelly R Calcagno, Howard C Crawford, Michael Leitges, Alan P Fields, Nicole R Murray
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3281025?pdf=render

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http://europepmc.org/articles/PMC3281025?pdf=render

Protein kinase C iota regulates pancreatic acinar-to-ductal metaplasia.

Internet

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