Acetylcholinesterase inhibition ameliorates retinal neovascularization and glial activation in oxygen-induced retinopathy

AIM: To investigate whether inhibition of acetylcholinesterase (AChE) by donepezil ameliorate aberrant retinal neovascularization (RNV) and abnormal glial activation in oxygen-induced retinopathy (OIR). METHODS: A mouse model of RNV was induced in postnatal day 7 (P7) mice by exposure to 75% oxygen...

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Bibliographic Details
Main Authors: Qiu-Ping Liu, Xian Zhang, Ya-Zhou Qin, Jing-Lin Yi, Jing-Ming Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2020-09-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2020/9/20200904.pdf