Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF-κB/TNF-α Signaling Pathway

Stem Cell-Derived Exosomes Prevent Aging-Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF-κB/TNF-α Signaling Pathway

Aging is a risk factor for cardiovascular disease, and there is no effective therapeutic approach to alleviate this condition. NF-κB and TNF-α have been implicated in the activation of the aging process, but the signaling molecules responsible for the inactivation of NF-κB and TNF-α remain unknown....

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Bibliographic Details
Main Authors: Bao Zhu, Lulu Zhang, Chun Liang, Bin Liu, Xiangbin Pan, Yanli Wang, Yuqing Zhang, Yu Zhang, Wenping Xie, Bing Yan, Feng Liu, Hon-Kan Yip, Xi-yong Yu, Yangxin Li
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/9739258

Internet

http://dx.doi.org/10.1155/2019/9739258

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