Identification of potential causal variants for premature ovarian failure by whole exome sequencing

Identification of potential causal variants for premature ovarian failure by whole exome sequencing

Abstract Background Premature ovarian failure (POF) is a highly heterogeneous disorder that occurs in 1% of women of reproductive age. Very few causative genes and variants contributing to POF have been detected, and the disease remains incompletely understood. In this study, we used whole exome seq...

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Bibliographic Details
Main Authors: Haengun Jin, JuWon Ahn, YoungJoon Park, JeongMin Sim, Han Sung Park, Chang Soo Ryu, Nam Keun Kim, KyuBum Kwack
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Medical Genomics
Subjects:
Premature ovarian failure
Whole exome sequencing
MCM8
MCM9
HFM1
Gene variants
Online Access:http://link.springer.com/article/10.1186/s12920-020-00813-x

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http://link.springer.com/article/10.1186/s12920-020-00813-x

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