Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients

Association between serum 25-hydroxyvitamin D and global DNA methylation in visceral adipose tissue from colorectal cancer patients

Abstract Background Visceral adipose tissue (VAT) has been identified as the essential fat depot for pathogenetic theories that associateobesity and colon cancer. LINE-1 hypomethylation has been mostly detected in tumor colon tissue, but less is known about the epigenetic pattern in surrounding tiss...

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Bibliographic Details
Main Authors: Daniel Castellano-Castillo, Sonsoles Morcillo, Ana B. Crujeiras, Lidia Sánchez-Alcoholado, Mercedes Clemente-Postigo, Esperanza Torres, Francisco José Tinahones, Manuel Macias-Gonzalez
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
Colorectal cancer
Global DNA methylation
Obesity
Epigenetic
Vitamin D
Online Access:http://link.springer.com/article/10.1186/s12885-018-5226-4

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http://link.springer.com/article/10.1186/s12885-018-5226-4

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