Toll-like receptor 7 agonist induces hypoplasia of the biliary system in a neonatal mouse model

Toll-like receptor 7 agonist induces hypoplasia of the biliary system in a neonatal mouse model

Background/Purpose: Viral infections and innate immunity signaling, especially Toll-like receptor 7 (TLR7) have been implicated in the pathogenesis of biliary atresia (BA). Administration of rhesus rotavirus-type A to newborn Balb/c mice produces inflammatory obstruction of bile ducts, which resembl...

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Bibliographic Details
Main Authors: Ying-Hsien Huang, Hsiang-Hung Shih, Mao-Meng Tiao, Chao-Cheng Huang, Kuang-Che Kuo, Fu-Chen Huang, Ya-Ling Yang, Jiin-Haur Chuang
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Journal of Microbiology, Immunology and Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118216300706

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http://www.sciencedirect.com/science/article/pii/S1684118216300706

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