Genetic Markers of White Matter Integrity in Schizophrenia Revealed by Parallel ICA

Genetic Markers of White Matter Integrity in Schizophrenia Revealed by Parallel ICA

It is becoming a consensus that white matter integrity is compromised in schizophrenia (SZ), however the underlying genetics remains elusive. Evidence suggests a polygenic basis of the disorder, which involves various genetic variants with modest individual effect sizes. In this work, we used a mult...

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Bibliographic Details
Main Authors: Cota Navin Gupta, Jiayu eChen, Jingyu eLiu, Eswar eDamaraju, Carrie eWright, Nora Irma Perrone-Bizzozero, Godfrey ePearlson, Li eLuo, Andrew M Michael, Jessica A Turner, Vince D Calhoun
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Human Neuroscience
Subjects:
Schizophrenia
Single nucleotide polymorphisms (SNPs)
Diffusion Tension Imaging (DTI)
Fractional Anisotropy (FA)
Parallel Independent Component Analysis (P-ICA)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00100/full

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http://journal.frontiersin.org/Journal/10.3389/fnhum.2015.00100/full

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