Metformin Adjunct With Antineoplastic Agents for the Treatment of Lung Cancer: A Meta-Analysis of Randomized Controlled Trials and Observational Cohort Studies

Metformin Adjunct With Antineoplastic Agents for the Treatment of Lung Cancer: A Meta-Analysis of Randomized Controlled Trials and Observational Cohort Studies

Objective: Resistance to anticancer agents ensures a poor prognosis in patients with lung cancer. Metformin could enhance the anticancer effects of standard antineoplastic agents [traditional chemotherapy drugs, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), or immune check...

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Bibliographic Details
Main Authors: Xiaofeng Luo, Xi Chen, Lin Wang, Bowen Yang, Shuang Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
metformin
chemotherapeutic drugs
lung cancer
survival
prognosis
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.639016/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.639016/full

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