Protective Role of Rabbit Nucleotide-Binding Oligomerization Domain-2 (NOD2)-Mediated Signaling Pathway in Resistance to Enterohemorrhagic Escherichia coli Infection

Protective Role of Rabbit Nucleotide-Binding Oligomerization Domain-2 (NOD2)-Mediated Signaling Pathway in Resistance to Enterohemorrhagic Escherichia coli Infection

Nucleotide-binding oligomerization domain 2 (NOD2), a member of the NOD-like receptors (NLRs) family that is well-known to play a key role in innate immune responses and is involved in innate antibacterial responses. In this study, rabbit NOD2 (rNOD2) was cloned from rabbit kidney (RK) cells. It was...

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Bibliographic Details
Main Authors: Mengjiao Guo, Rong Li, Qianqian Xiao, Xiuxiu Fan, Ning Li, Yingli Shang, Liangmeng Wei, Tongjie Chai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
rabbits
NOD2
NF-κB
antibacterial ability
EHEC
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00220/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00220/full

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