Efficacy of nano‐particulated, water‐soluble erlotinib against intracranial metastases of EGFR‐mutant lung cancer

Efficacy of nano‐particulated, water‐soluble erlotinib against intracranial metastases of EGFR‐mutant lung cancer

Central nervous system (CNS) metastasis is one of the serious complications of epidermal growth factor receptor (EGFR)‐mutant lung cancer, which arises due to poor penetration of the brain–blood barrier by EGFR‐tyrosine kinase inhibitors (EGFR‐TKIs). Although osimertinib, a third‐generation EGFR‐TKI...

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Bibliographic Details
Main Authors: Dong Ha Kim, Yun Jung Choi, Ki Jung Sung, Seon‐A Yoo, Young Hoon Sung, Jeong Kon Kim, Chang‐Min Choi, Miyong Yun, Eun Yong Lee, Yong Suk Jin, Seungho Cook, Jin Kyung Rho, Jae Cheol Lee
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:Molecular Oncology
Subjects:
brain metastasis
EGFR‐TKI
lung cancer
nano‐particulation
NUFS‐sErt
Online Access:https://doi.org/10.1002/1878-0261.12394

Internet

https://doi.org/10.1002/1878-0261.12394

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