Impact of host genes and strand selection on miRNA and miRNA* expression.

Dysregulation of miRNAs expression plays a critical role in the pathogenesis of genetic, multifactorial disorders and in human cancers. We exploited sequence, genomic and expression information to investigate two main aspects of post-transcriptional regulation in miRNA biogenesis, namely strand sele...

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Bibliographic Details
Main Authors: Marta Biasiolo, Gabriele Sales, Marta Lionetti, Luca Agnelli, Katia Todoerti, Andrea Bisognin, Alessandro Coppe, Chiara Romualdi, Antonino Neri, Stefania Bortoluzzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21909367/?tool=EBI