Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in vitro and in vivo Models of Neurodegenerative Diseases

Octadecaneuropeptide (ODN) and its precursor diazepam-binding inhibitor (DBI) are peptides belonging to the family of endozepines. Endozepines are exclusively produced by astroglial cells in the central nervous system of mammals, and their release is regulated by stress signals and neuroactive compo...

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Bibliographic Details
Main Authors: Olfa Masmoudi-Kouki, Amira Namsi, Yosra Hamdi, Seyma Bahdoudi, Ikram Ghouili, Julien Chuquet, Jérôme Leprince, Benjamin Lefranc, Taoufik Ghrairi, Marie-Christine Tonon, Gérard Lizard, David Vaudry
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Endocrinology
Subjects:
gliopeptide ODN
neurodegeneration
cell protection
cell differentiation
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.566026/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.566026/full

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