Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception
Abstract Background The well-established association of chronological age with changes in DNA methylation is primarily founded on the analysis of large sets of blood samples, while conclusions regarding tissue-specificity are typically based on small number of samples, tissues and CpGs. Here, we sys...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
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Series: | Epigenetics & Chromatin |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13072-018-0191-3 |