Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

Abstract Background The well-established association of chronological age with changes in DNA methylation is primarily founded on the analysis of large sets of blood samples, while conclusions regarding tissue-specificity are typically based on small number of samples, tissues and CpGs. Here, we sys...

Full description

Bibliographic Details
Main Authors: Roderick C. Slieker, Caroline L. Relton, Tom R. Gaunt, P. Eline Slagboom, Bastiaan T. Heijmans
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-018-0191-3