Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times

Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times

Dopamine (DA) neurons are thought to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulated VTA DA neurons in mice during fear exti...

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Bibliographic Details
Main Authors: Lili X Cai, Katherine Pizano, Gregory W Gundersen, Cameron L Hayes, Weston T Fleming, Sebastian Holt, Julia M Cox, Ilana B Witten
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
dopamine
vta
fear
extinction
optogenetics
fiber photometry
Online Access:https://elifesciences.org/articles/54936

Internet

https://elifesciences.org/articles/54936

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