Micromolar Valproic Acid Doses Preserve Survival and Induce Molecular Alterations in Neurodevelopmental Genes in Two Strains of Zebrafish Larvae

Autism spectrum disorders (ASDs) comprise a genetically heterogeneous group of conditions characterized by a multifaceted range of impairments and multifactorial etiology. Epidemiological studies have identified valproic acid (VPA), an anticonvulsant used to treat epilepsy, as an environmental facto...

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Bibliographic Details
Main Authors: Andrea Messina, Alessandra Boiti, Valeria Anna Sovrano, Paola Sgadò
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
VPA
Online Access:https://www.mdpi.com/2218-273X/10/10/1364