Efficacy of Bioactive Cyclic Peptides in Rheumatoid Arthritis: Translation from In Vitro to In Vivo Models

Using a novel drug discovery technology reported in previous issues of this journal cyclic peptides have been created which are able to down-regulate secretion of inflammatory cytokines, in vitro, by stimulated cells of the macrophage cell line J774. The cytokines in question, TNF-alpha and IL-6, ar...

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Bibliographic Details
Main Authors: Roger New, Michal Bogus, Gurpal S. Bansal, Malgorzata Dryjska, Katarzyna Zajkowska, Michael Burnet
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Molecules
Subjects:
TNF
Online Access:https://www.mdpi.com/1420-3049/22/10/1613