Sulforaphane Promotes Dendritic Cell Stimulatory Capacity Through Modulation of Regulatory Molecules, JAK/STAT3- and MicroRNA-Signaling

Sulforaphane Promotes Dendritic Cell Stimulatory Capacity Through Modulation of Regulatory Molecules, JAK/STAT3- and MicroRNA-Signaling

IntroductionThe broccoli isothiocyanate sulforaphane was shown to inhibit inflammation and tumor progression, also in pancreatic cancer, while its effect on tumor immunity is poorly understood. We investigated the immunoregulatory effect of sulforaphane on human dendritic cells alone and in presence...

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Bibliographic Details
Main Authors: Yangyi Wang, Emilia Petrikova, Wolfgang Gross, Carsten Sticht, Norbert Gretz, Ingrid Herr, Svetlana Karakhanova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
sulforaphane
dendritic cells
T cells
regulatory molecules
STAT3
miRNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.589818/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.589818/full

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