Optoregulated force application to cellular receptors using molecular motors

Molecular scale force application in physiological environments is important for studying mechanotransduction. Here, the authors use a molecular machine to apply forces at cell-matrix and cell-cell junctions using light to trigger twisting actuation which then pulls on cell membrane receptors.

Bibliographic Details
Main Authors: Yijun Zheng, Mitchell K. L. Han, Renping Zhao, Johanna Blass, Jingnan Zhang, Dennis W. Zhou, Jean-Rémy Colard-Itté, Damien Dattler, Arzu Çolak, Markus Hoth, Andrés J. García, Bin Qu, Roland Bennewitz, Nicolas Giuseppone, Aránzazu del Campo
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23815-4