Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

Sex chromosomes drive gene expression and regulatory dimorphisms in mouse embryonic stem cells

Abstract Background Pre-implantation embryos exhibit sexual dimorphisms in both primates and rodents. To determine whether these differences reflected sex-biased expression patterns, we generated transcriptome profiles for six 40,XX, six 40,XY, and two 39,X mouse embryonic stem (ES) cells by RNA seq...

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Bibliographic Details
Main Authors: Rachael J. Werner, Bryant M. Schultz, Jacklyn M. Huhn, Jaroslav Jelinek, Jozef Madzo, Nora Engel
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Biology of Sex Differences
Subjects:
Sex chromosomes
Transcriptome
Embryonic stem cells
Transcription factors
Epigenetic enzymes
Online Access:http://link.springer.com/article/10.1186/s13293-017-0150-x

Internet

http://link.springer.com/article/10.1186/s13293-017-0150-x

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