Snapin Recruits Dynein to BDNF-TrkB Signaling Endosomes for Retrograde Axonal Transport and Is Essential for Dendrite Growth of Cortical Neurons

Neurotrophin signaling is crucial for neuron growth. While the “signaling endosomes” hypothesis is one of the accepted models, the molecular machinery that drives retrograde axonal transport of TrkB signaling endosomes is largely unknown. In particular, mechanisms recruiting dynein to TrkB signalin...

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Bibliographic Details
Main Authors: Bing Zhou, Qian Cai, Yuxiang Xie, Zu-Hang Sheng
Format: Article
Language:English
Published: Elsevier 2012-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712001702