Inhibition of Pancreatic α-amylase by Resveratrol Derivatives: Biological Activity and Molecular Modelling Evidence for Cooperativity between Viniferin Enantiomers

Inhibition of Pancreatic α-amylase by Resveratrol Derivatives: Biological Activity and Molecular Modelling Evidence for Cooperativity between Viniferin Enantiomers

To improve the current understanding of the role of stilbenoids in the management of diabetes, the inhibition of the pancreatic α-amylase by resveratrol derivatives was investigated. To approach in a systematic way, the mechanistic and structural aspects of the interaction, potential bioact...

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Bibliographic Details
Main Authors: Luce M. Mattio, Mauro Marengo, Chiara Parravicini, Ivano Eberini, Sabrina Dallavalle, Francesco Bonomi, Stefania Iametti, Andrea Pinto
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
resveratrol
stilbenoids
pancreatic alpha-amylase
enzyme inhibition
molecular docking
food bioactives synergism
Online Access:https://www.mdpi.com/1420-3049/24/18/3225

Internet

https://www.mdpi.com/1420-3049/24/18/3225

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