Epistasis for growth rate and total metabolic flux in yeast.

Studies of interactions between gene deletions repeatedly show that the effect of epistasis on the growth of yeast cells is roughly null or barely positive. These observations relate generally to the pace of growth, its costs in terms of required metabolites and energy are unknown. We measured the m...

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Bibliographic Details
Main Authors: Agata Jakubowska, Ryszard Korona
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295780?pdf=render