Optimization and evaluation of astragalus polysaccharide injectable thermoresponsive in-situ gels.

The objective of this study was to develop an injectable in situ forming gel system based on Poloxamer for sustained release of Astragalus polysaccharide (APS), thus achieved once or twice administration instead of frequent dosing during long-term treatment. The optimal formulation is 10 g APS, 18 g...

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Bibliographic Details
Main Authors: Zugong Yu, Fanxi Guo, Yangyang Guo, Zhenrui Zhang, Feng Wu, Xiaoqing Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5369758?pdf=render