Hybrid Dynamic Optimization Methods for Systems Biology with Efficient Sensitivities

In recent years, model optimization in the field of computational biology has become a prominent area for development of pharmaceutical drugs. The increased amount of experimental data leads to the increase in complexity of proposed models. With increased complexity comes a necessity for computation...

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Bibliographic Details
Main Authors: Nicholas R. Lewis, John D. Hedengren, Eric L. Haseltine
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Processes
Subjects:
Online Access:http://www.mdpi.com/2227-9717/3/3/701