An efficient pipeline for ancient DNA mapping and recovery of endogenous ancient DNA from whole‐genome sequencing data

An efficient pipeline for ancient DNA mapping and recovery of endogenous ancient DNA from whole‐genome sequencing data

Abstract Ancient DNA research has developed rapidly over the past few decades due to improvements in PCR and next‐generation sequencing (NGS) technologies, but challenges still exist. One major challenge in relation to ancient DNA research is to recover genuine endogenous ancient DNA sequences from...

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Bibliographic Details
Main Authors: Wenhao Xu, Yu Lin, Keliang Zhao, Haimeng Li, Yinping Tian, Jacob Njaramba Ngatia, Yue Ma, Sunil Kumar Sahu, Huabing Guo, Xiaosen Guo, Yan Chun Xu, Huan Liu, Karsten Kristiansen, Tianming Lan, Xinying Zhou
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Ecology and Evolution
Subjects:
ancient DNA
BWA mem
deamination
DNA damage
genome mapping
Online Access:https://doi.org/10.1002/ece3.7056

Internet

https://doi.org/10.1002/ece3.7056

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