A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection.

A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection.

Approximately 200 million people throughout the world are infected with hepatitis C virus (HCV). One of the most striking features of HCV infection is its high propensity to establish persistence (approximately 70-80%) and progressive liver injury. Galectins are evolutionarily conserved glycan-bindi...

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Bibliographic Details
Main Authors: John A Mengshol, Lucy Golden-Mason, Tomohiro Arikawa, Maxwell Smith, Toshiro Niki, Ryan McWilliams, Jessica A Randall, Rachel McMahan, Michael A Zimmerman, Manu Rangachari, Evgenia Dobrinskikh, Pierre Busson, Stephen J Polyak, Mitsuomi Hirashima, Hugo R Rosen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2831996?pdf=render

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http://europepmc.org/articles/PMC2831996?pdf=render

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