AD-LIBS: inferring ancestry across hybrid genomes using low-coverage sequence data

Abstract Background Inferring the ancestry of each region of admixed individuals’ genomes is useful in studies ranging from disease gene mapping to speciation genetics. Current methods require high-coverage genotype data and phased reference panels, and are therefore inappropriate for many data sets...

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Bibliographic Details
Main Authors: Nathan K. Schaefer, Beth Shapiro, Richard E. Green
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1613-0