Lower Functional Connectivity of the Periaqueductal Gray Is Related to Negative Affect and Clinical Manifestations of Fibromyalgia

Lower Functional Connectivity of the Periaqueductal Gray Is Related to Negative Affect and Clinical Manifestations of Fibromyalgia

Fibromyalgia (FM) syndrome is characterized by chronic widespread pain, muscle tenderness and emotional distress. Previous studies found reduced endogenous pain modulation in FM. This deficiency of pain modulation may be related to the attributes of chronic pain and other clinical symptoms experienc...

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Bibliographic Details
Main Authors: Marie-Andrée Coulombe, Keith St. Lawrence, Dwight E. Moulin, Patricia Morley-Forster, Mahsa Shokouhi, Warren R. Nielson, Karen D. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Neuroanatomy
Subjects:
functional magnetic resonance imaging
periaqueductal gray
resting-state fMRI
functional connectivity
descending pain modulation
fibromyalgia
Online Access:http://journal.frontiersin.org/article/10.3389/fnana.2017.00047/full

Internet

http://journal.frontiersin.org/article/10.3389/fnana.2017.00047/full

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