Alternative splicing of TAF6: downstream transcriptome impacts and upstream RNA splice control elements.

The TAF6δ pathway of apoptosis can dictate life versus death decisions independently of the status of p53 tumor suppressor. TAF6δ is an inducible pro-apoptotic subunit of the general RNA polymerase II (Pol II) transcription factor TFIID. Alternative splice site choice of TAF6δ has been shown to be a...

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Bibliographic Details
Main Authors: Catherine Kamtchueng, Marie-Éve Stébenne, Aurélie Delannoy, Emmanuelle Wilhelm, Hélène Léger, Arndt G Benecke, Brendan Bell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4099370?pdf=render