MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway

MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway

Summary: The immune system is not only required for preventing threats exerted by pathogens but also essential for developing immune tolerance to avoid tissue damage. This study identifies a distinct mechanism by which MYSM1 suppresses innate immunity and autoimmunity. The expression of MYSM1 is ind...

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Bibliographic Details
Main Authors: Mingfu Tian, Weiyong Liu, Qi Zhang, Yuqing Huang, Wen Li, Wenbiao Wang, Peiyi Zhao, Shanyu Huang, Yunting Song, Muhammad Adnan Shereen, Mengying Qin, Yingle Liu, Kailang Wu, Jianguo Wu
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Cell Reports
Subjects:
adenovirus
ADV
autoimmune disease
autoimmunity
cyclic GMP-AMP synthase
cGAS
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720312869

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http://www.sciencedirect.com/science/article/pii/S2211124720312869

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