Effect of amitriptyline on lipid deposition and biochemical metabolism in a cell model of nonalcoholic fatty liver disease

ObjectiveTo investigate the effect of amitriptyline on lipid deposition and biochemical metabolism in a cell model of nonalcoholic fatty liver disease (NAFLD) by regulating the acid sphingomyelinase (ASM)/ceramide (CE) pathway. MethodsHepG2 and L02 cells were cultured in vitro to establish a cell mo...

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Bibliographic Details
Main Author: LIU Qin
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2021-01-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/cn/article/doi/10.3969/j.issn.1001-5256.2021.01.020