Muscle Microbiopsy to Delineate Stem Cell Involvement in Young Patients: A Novel Approach for Children With Cerebral Palsy

Muscle Microbiopsy to Delineate Stem Cell Involvement in Young Patients: A Novel Approach for Children With Cerebral Palsy

Cerebral palsy (CP), the single largest cause of childhood physical disability, is characterized firstly by a lesion in the immature brain, and secondly by musculoskeletal problems that progress with age. Previous research reported altered muscle properties, such as reduced volume and satellite cell...

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Bibliographic Details
Main Authors: Marlies Corvelyn, Nathalie De Beukelaer, Robin Duelen, Jorieke Deschrevel, Anja Van Campenhout, Sandra Prinsen, Ghislaine Gayan-Ramirez, Karen Maes, Guido Weide, Kaat Desloovere, Maurilio Sampaolesi, Domiziana Costamagna
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
cerebral palsy
young children
muscle microbiopsy
adult muscle stem cell-derived progenitors
differentiation potential
myogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00945/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00945/full

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