Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

Objective: To identify and validate circulating micro RNAs (miRNAs) that mark gene expression changes in articular cartilage early in osteoarthritis (OA) pathophysiology process. Methods: Within the ongoing RAAK study, human preserved OA cartilage and plasma (<i>N</i> = 22 paired samples...

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Bibliographic Details
Main Authors: Yolande F. M. Ramos, Rodrigo Coutinho de Almeida, Nico Lakenberg, Eka Suchiman, Hailiang Mei, Margreet Kloppenburg, Rob G. H. H. Nelissen, Ingrid Meulenbelt
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
circulating microRNAs
osteoarthritis
biomarker
Online Access:https://www.mdpi.com/2218-273X/11/9/1356

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https://www.mdpi.com/2218-273X/11/9/1356

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