HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis

HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis

Abstract Diabetic nephropathy (DN) is a serious complication in type 1 and type 2 diabetes, and renal interstitial fibrosis plays a key role in DN progression. Here, we aimed to probe into the role and potential mechanism of miR-483-5p in DN-induced renal interstitial fibrosis. In this study, we cor...

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Bibliographic Details
Main Authors: DongWei Liu, FengXun Liu, ZhengYong Li, ShaoKang Pan, JunWei Xie, ZiHao Zhao, ZhenJie Liu, JiaHui Zhang, ZhangSuo Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03460-x

Internet

https://doi.org/10.1038/s41419-021-03460-x

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